

| Catalog No. | MB647012 |
|---|---|
| Description |
Mouse MX1 Recombinant Protein (N-His) (MB647012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE. by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q3UD61 |
| Protein length | Met1-Asp226 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Mus musculus (Mouse) |
| Nature | Recombinant |
| Endotoxin level | Remove endotoxin and sterilization is required for cell assay. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 26.76 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | IFI-78K, Interferon-induced GTP-binding protein Mx1, Interferon-induced GTP-binding protein Mx1, N-terminally processed, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA, MX1, Myxoma resistance protein 1, Myxovirus resistance protein 1 |
| Background | Interferon-induced GTP-binding protein Mx1 is a ~75 kDa protein. Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. |
| Note | For research use only |
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