Human Complement C5 Recombinant Protein (C-His) (HF687011)

Name: Human Complement C5 Recombinant Protein (C-His)
Brand: abinScience
SKU: HF687011
Price: 298 USD
Availability: InStock

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SDS

Overview

Catalog No.	HF687011
Description	Human Complement C5 Recombinant Protein (C-His) (HF687011) expressed in Mammalian Cells. Purity: >90% as determined by SDS-PAGE. by SDS-PAGE. Highlights ●Recombinant — Consistent lot-to-lot performance. ●High Purity — >90% as determined by SDS-PAGE. by SDS-PAGE for demanding downstream applications.
Expression system	Mammalian Cells
Accession	P01031
Protein length	Gln19-Cys1676
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	<0.1 EU/ug as determined by LAL method.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	189.24 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5, C5a anaphylatoxin, CPAMD4, Complement C5, Complement C5 alpha chain, Complement C5 alpha' chain, Complement C5 beta chain, Complement C5b
Background	Complement C5 is a ~188 kDa protein. Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Activated downstream of classical, alternative, lectin and GZMK complement pathways. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 3. Heesterbeek, DA. et al. (2019) The EMBO journal 38. PMID: 30643019 4. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279 5. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 6. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882
Note	For research use only

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SDS-PAGE

SDS-PAGE for Human Complement C5 Recombinant Protein (C-His)

References

Datasheet

Human Complement C5 Recombinant Protein (C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Human Complement C5 Recombinant Protein (C-His) (HF687011)

Overview

Images

References

Datasheet

SDS