Anti-763.74 Monoclonal Recombinant Antibody (MK2-23) (AV349013)

Name: Anti-763.74 Monoclonal Recombinant Antibody (MK2-23)
Brand: abinScience
SKU: AV349013
Price: 888 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

AV349013

Applications

ELISA

Host species

Mouse

Isotype

IgG2a

Clone ID

MK2-23

Clonality

Monoclonal

Target

HMW-MAA mimicry, Anti-Human CSPG4/HMW-MAA/MCSP/NG2 Antibody clone 763.74#, Idiotypic antibody

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q6UVK1

RRID

Anti-763.74 Monoclonal Antibody (MK2-23) (abinScience Cat# AV349013, RRID:AB_3727893)
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Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Chondroitin sulfate proteoglycan 4 (763.74 (CSPG4)) is a ~250 kDa protein. Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties.

Note

For research use only.

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