Anti-ABCD3 Polyclonal Antibody (HB262014)

Name: Anti-ABCD3 Polyclonal Antibody
Brand: abinScience
SKU: HB262014
Price: 168 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HB262014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human ABCD3 (Pro425-Ser659).

Target

ABCD3, 70 kDa peroxisomal membrane protein, ATP-binding cassette sub-family D member 3, PXMP1, PMP70

Purification

Purified by antigen affinity column.

Accession

P28288

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

ATP-binding cassette sub-family D member 3 (ABCD3) is a ~75 kDa protein. Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation.

1. Roerig, P. et al. (2001) FEBS letters 492, 66-72. PMID: 11248239

2. van Roermund, CW. et al. (2014) Biochimica et biophysica acta 1841, 563-8. PMID: 24333844

3. Ferdinandusse, S. et al. (2015) Human molecular genetics 24, 361-70. PMID: 25168382

4. Okamoto, T. et al. (2018) Biochemical and biophysical research communications 496, 1122-1127. PMID: 29397936

5. Vaca Jacome, AS. et al. (2015) Proteomics 15, 2519-24. PMID: 25944712

Note

For research use only.

Images

References

Datasheet

Anti-ABCD3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-ABCD3 Polyclonal Antibody (HB262014)

Overview

Images

References

Datasheet

SDS

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