Anti-ABCG4 Polyclonal Antibody (HP927014)

Name: Anti-ABCG4 Polyclonal Antibody
Brand: abinScience
SKU: HP927014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HP927014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human ABCG4 (Val59-Thr301).

Target

ATP-binding cassette sub-family G member 4, ABCG4, WHITE2

Purification

Purified by antigen affinity column.

Accession

Q9H172

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

ATP-binding cassette sub-family G member 4 (ABCG4) is a ~71 kDa protein. ATP-dependent transporter of the ATP-binding cassette (ABC) family that may be involved in the cellular efflux of sterols, in particular cholesterol and desmosterol (a cholesterol precursor), to high-density lipoprotein (HDL). May play an important role in the removal of amyloid-beta peptides from brain, in a process that can be antagonized by desmosterol. However it is unclear whether ABCG4 can directly transport amyloid-beta peptides or whether peptide export may be facilitated due to changes in the membrane lipid environment. Induces apoptosis in various cells.

1. Cserepes, J. et al. (2004) Biochemical and biophysical research communications 320, 860-7. PMID: 15240127

2. Yang, A. et al. (2021) Biochimica et biophysica acta. General subjects 1865, 129769. PMID: 33141061

3. Hegyi, Z. et al. (2016) PloS one 11, e0156516. PMID: 27228027

Note

For research use only.

Images

References

Datasheet

Anti-ABCG4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-ABCG4 Polyclonal Antibody (HP927014)

Overview

Images

References

Datasheet

SDS

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