

| Catalog No. | HV651014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human ACSS1 (Phe517-Lys689). | ||||||||
| Target | Acetyl-CoA synthetase 2, ACSS1, ACAS2L, Acetate--CoA ligase 2, Propionate--CoA ligase, KIAA1846, AceCS2, Acetyl-coenzyme A synthetase 2-like, mitochondrial, Acyl-CoA synthetase short-chain family member 1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9NUB1 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Acetyl-coenzyme A synthetase 2-like, mitochondrial (ACSS1) is a ~74 kDa protein. Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions. Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient. 1. Schwer, B. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 10224-10229. PMID: 16788062 | ||||||||
| Note | For research use only. |
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