Anti-ADAM15/MDC15 Polyclonal Antibody (HC558014)

Name: Anti-ADAM15/MDC15 Polyclonal Antibody
Brand: abinScience
SKU: HC558014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC558014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ADAM15/MDC15 (Pro46-Asp171).

Target

Disintegrin and metalloproteinase domain-containing protein 15, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15, ADAM15, MDC15, Metalloprotease RGD disintegrin protein, Metargidin, MDC-15, ADAM 15

Purification

Purified by antigen affinity column.

Accession

Q13444

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Disintegrin and metalloproteinase domain-containing protein 15 (ADAM15/MDC15) is a ~92 kDa protein. Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-ADAM15/MDC15 polyclonal antibody at 1ug/mL on recombinant ADAM15/MDC15 (Catalog No. HC558022).

References

Datasheet