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Anti-ADCY5 Polyclonal Antibody (HF975014)

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Overview
Catalog No.HF975014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human ADCY5 (Ser1066-Ser1261).
Target AC5, ATP pyrophosphate-lyase 5, Adenylate cyclase type 5, Adenylate cyclase type V, Adenylyl cyclase 5, ADCY5
Purification Purified by antigen affinity column.
Accession O95622
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Adenylate cyclase type 5 (ADCY5) is a ~138 kDa protein. Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion.

1. Ding, Q. et al. (2004) Molecular pharmacology 66, 921-8. PMID: 15385642
2. Chen, YZ. et al. (2014) Annals of neurology 75, 542-9. PMID: 24700542
3. Brand, CS. et al. (2015) Molecular pharmacology 88, 758-67. PMID: 26206488
4. Hodson, DJ. et al. (2014) Diabetes 63, 3009-21. PMID: 24740569
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-ADCY5 Polyclonal Antibody

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