Anti-ADCY6 Polyclonal Antibody (HT259014)

Name: Anti-ADCY6 Polyclonal Antibody
Brand: abinScience
SKU: HT259014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT259014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ADCY6 (Gln373-Gly579).

Target

Adenylate cyclase type 6, KIAA0422, ATP pyrophosphate-lyase 6, ADCY6, Adenylyl cyclase 6, Ca(2+)-inhibitable adenylyl cyclase, Adenylate cyclase type VI

Purification

Purified by antigen affinity column.

Accession

O43306

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Adenylate cyclase type 6 (ADCY6) is a ~130 kDa protein. Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors. Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells. Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion.

1. Gao, X. et al. (2007) The Journal of biological chemistry 282, 294-302. PMID: 17110384

2. Gros, R. et al. (2007) Arteriosclerosis, thrombosis, and vascular biology 27, 2657-63. PMID: 17916776

Note

For research use only.

Images

Western blot

Lane 1: Hela cell lysate
Lane 2: PC-3 cell lysate

References

Datasheet

Anti-ADCY6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-ADCY6 Polyclonal Antibody (HT259014)

Overview

Images

References

Datasheet

SDS

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