Anti-Adiponectin/ACRP30/ADIPOQ Polyclonal Antibody (HS862014)

Name: Anti-Adiponectin/ACRP30/ADIPOQ Polyclonal Antibody
Brand: abinScience
SKU: HS862014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HS862014

Description

Anti-Adiponectin/ACRP30/ADIPOQ Polyclonal Antibody (HS862014) is a rabbit polyclonal antibody detecting Adiponectin in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human Adiponectin/ACRP30/ADIPOQ (Glu19-Asn244).

Target

Adiponectin, ACRP30, GBP28, Adipose most abundant gene transcript 1 protein, ACDC, APM1, ADIPOQ, apM-1, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein, Gelatin-binding protein

Purification

Purified by antigen affinity column.

Accession

Q15848

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Adiponectin (ADPN) is a ~26 kDa protein. Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Adiponectin/ACRP30/ADIPOQ polyclonal antibody at 1ug/mL on recombinant Adiponectin/ACRP30/ADIPOQ (Catalog No. HS862012).

References

Datasheet