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Anti-ADIPOR1 Polyclonal Antibody (HV630014)

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Overview
Catalog No.HV630014
Description
Anti-ADIPOR1 Polyclonal Antibody (HV630014) is a rabbit polyclonal antibody detecting Adiponectin receptor protein 1; Progestin and adipoQ receptor family member 1; Progestin and adipoQ receptor family member I; ADIPOR1; PAQR1; TESBP1A; CGI-45 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant human ADIPOR1 (Ser2-Gly136).
Target Adiponectin receptor protein 1; Progestin and adipoQ receptor family member 1; Progestin and adipoQ receptor family member I; ADIPOR1; PAQR1; TESBP1A; CGI-45
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q96A54, Q91VH1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Adiponectin receptor protein 1 (ADIPOR1) is a ~42 kDa protein. Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin.

1. Yamauchi, T. et al. (2003) Nature 423, 762-9. PMID: 12802337
2. Tanabe, H. et al. (2015) Nature 520, 312-316. PMID: 25855295
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
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