

| Catalog No. | HV258014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-ADIPOR2 Polyclonal Antibody (HV258014) is a rabbit polyclonal antibody detecting ADIPOR2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human ADIPOR2 (Met1-Gly147). | ||||||||
| Target | Adiponectin receptor protein 2, ADIPOR2, PAQR2, Progestin and adipoQ receptor family member 2, Progestin and adipoQ receptor family member II | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q86V24 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Adiponectin receptor protein 2 (ADIPOR2) is a ~43 kDa protein. Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels. 1. Yamauchi, T. et al. (2003) Nature 423, 762-9. PMID: 12802337 2. Tanabe, H. et al. (2015) Nature 520, 312-316. PMID: 25855295 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-ADIPOR2 polyclonal antibody at 1ug/mL on recombinant ADIPOR2 (Catalog No. HV258012).
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