Anti-ALDH1A2 Polyclonal Antibody (HF656014)

Name: Anti-ALDH1A2 Polyclonal Antibody
Brand: abinScience
SKU: HF656014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HF656014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ALDH1A2 (Met1-Val422).

Target

Retinaldehyde-specific dehydrogenase type 2, ALDH1A2, Retinal dehydrogenase 2, RALDH2, RALDH(II), Aldehyde dehydrogenase family 1 member A2, RALDH 2, RalDH2

Purification

Purified by antigen affinity column.

Accession

O94788

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Retinal dehydrogenase 2 (ALDH1A2) is a ~56 kDa protein. Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively. Retinoate signaling is critical for the transcriptional control of many genes, for instance it is crucial for initiation of meiosis in both male and female (Probable). Recognizes retinal as substrate, both in its free form and when bound to cellular retinol-binding protein. Can metabolize octanal and decanal, but has only very low activity with benzaldehyde, acetaldehyde and propanal. Displays complete lack of activity with citral.

1. Chen, Y. et al. (2018) ACS chemical biology 13, 582-590. PMID: 29240402

2. Beecroft, SJ. et al. (2021) Human mutation 42, 506-519. PMID: 33565183

Note

For research use only.

Images

References

Datasheet

Anti-ALDH1A2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-ALDH1A2 Polyclonal Antibody (HF656014)

Overview

Images

References

Datasheet

SDS

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