Anti-ALDH7A1 Polyclonal Antibody (HW546014)

Name: Anti-ALDH7A1 Polyclonal Antibody
Brand: abinScience
SKU: HW546014
Price: 96 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW546014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human ALDH7A1 (Met1-Gln539).

Target

ALDH7A1, Delta1-piperideine-6-carboxylate dehydrogenase, Antiquitin-1, P6c dehydrogenase, Alpha-AASA dehydrogenase, Alpha-aminoadipic semialdehyde dehydrogenase, Aldehyde dehydrogenase family 7 member A1, Betaine aldehyde dehydrogenase, ATQ1

Purification

Purified by antigen affinity column.

Accession

P49419

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) is a ~58 kDa protein. Aldehyde dehydrogenase enzyme that mediates important protective effects. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in cellular defense against hyperosmotic stress by metabolizing betaine aldehyde to betaine, an important cellular osmolyte and methyl donor.

1. Mills, PB. et al. (2006) Nature medicine 12, 307-9. PMID: 16491085

2. Brocker, C. et al. (2010) The Journal of biological chemistry 285, 18452-63. PMID: 20207735

3. Mills, PB. et al. (2010) Brain : a journal of neurology 133, 2148-59. PMID: 20554659

4. Brocker, C. et al. (2011) Chemico-biological interactions 191, 269-77. PMID: 21338592

5. Luo, M. et al. (2015) ACS chemical biology 10, 693-7. PMID: 25554827

6. Laciak, AR. et al. (2020) The FEBS journal 287, 173-189. PMID: 31302938

7. Laciak, AR. et al. (2020) Journal of inherited metabolic disease 43, 635-644. PMID: 31652343

8. Korasick, DA. et al. (2024) Chemico-biological interactions 394, 110993. PMID: 38604394

9. Yang, JS. et al. (2025) Cell 188, 2569-2585.e20. PMID: 40233740

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-ALDH7A1 polyclonal antibody at 1µg/ml on various samples.
Lane 1: 293T cell lysate
Lane 2: Mouse liver lysate
Lane 3: Rat liver lysate
Lane 4: Rat kidney lysate

References

Datasheet

Anti-ALDH7A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-ALDH7A1 Polyclonal Antibody (HW546014)

Overview

Images

References

Datasheet

SDS

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