Anti-AOC1/DAO Polyclonal Antibody (HB958014)

Name: Anti-AOC1/DAO Polyclonal Antibody
Brand: abinScience
SKU: HB958014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HB958014

Description

Anti-AOC1/DAO Polyclonal Antibody (HB958014) is a rabbit polyclonal antibody detecting AOC1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human AOC1/DAO (Glu20-Trp322).

Target

AOC1, ABP1, DAO, Kidney amine oxidase, Histaminase, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein 1, Diamine oxidase, KAO, DAO1, Amine oxidase copper domain-containing protein 1

Purification

Purified by antigen affinity column.

Accession

P19801

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Diamine oxidase [copper-containing] (AOC1/DAO) is a ~85 kDa protein. Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Its preferred substrates are the diamines histamine and 1-methylhistamine and it could therefore play a role in allergic and immune responses. Has a broad specificity for diamines and can also act on cadaverine and putrescine, two products of amino acid catabolism. It could also act on polyamines, like spermidine and spermine though less efficiently, and regulate various biological processes.

1. Elmore, BO. et al. (2002) Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 7, 565-79. PMID: 12072962

2. McGrath, AP. et al. (2009) Biochemistry 48, 9810-22. PMID: 19764817

3. Hölttä, E. et al. (1975) The Biochemical journal 145, 373-8. PMID: 239684

4. Novotny, WF. et al. (1994) The Journal of biological chemistry 269, 9921-5. PMID: 8144586

Note

For research use only.

Images

References

Datasheet

Anti-AOC1/DAO Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-AOC1/DAO Polyclonal Antibody (HB958014)

Overview

Images

References

Datasheet

SDS

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