Anti-AQP1 Polyclonal Antibody (HB219014)

Name: Anti-AQP1 Polyclonal Antibody
Brand: abinScience
SKU: HB219014
Price: 96 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

20ug
50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB219014

Description

Anti-AQP1 Polyclonal Antibody (HB219014) is a rabbit polyclonal antibody detecting AQP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human AQP1 (Val201-Lys269).

Target

Aquaporin-CHIP, Urine water channel, AQP-1, Aquaporin-1, AQP1, CHIP28, Water channel protein for red blood cells and kidney proximal tubule

Purification

Purified by antigen affinity column.

Accession

P29972

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Aquaporin-1 (AQP1) is a ~28 kDa protein. Forms a water channel that facilitates the transport of water across cell membranes, playing a crucial role in water homeostasis in various tissues. Could also be permeable to small solutes including hydrogen peroxide, glycerol and gases such as amonnia (NH3), nitric oxide (NO) and carbon dioxide (CO2). Recruited to the ankyrin-1 complex, a multiprotein complex of the erythrocyte membrane, it could be part of a CO2 metabolon, linking facilitated diffusion of CO2 across the membrane, anion exchange of Cl(-)/HCO3(-) and interconversion of dissolved CO2 and carbonic acid in the cytosol. In vitro, it shows non-selective gated cation channel activity and may be permeable to cations like K(+) and Na(+) in vivo.

1. Preston, GM. et al. (1992) Science (New York, N.Y.) 256, 385-7. PMID: 1373524

2. Rungaldier, S. et al. (2013) Biochimica et biophysica acta 1828, 956-66. PMID: 23219802

3. Herrera, M. et al. (2006) Hypertension (Dallas, Tex. : 1979) 48, 157-64. PMID: 16682607

4. Endeward, V. et al. (2006) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20, 1974-81. PMID: 17012249

5. Musa-Aziz, R. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 5406-11. PMID: 19273840

6. Montiel, V. et al. (2020) Science translational medicine 12. PMID: 33028705

7. Abrami, L. et al. (1996) Pflugers Archiv : European journal of physiology 431, 408-14. PMID: 8584435

8. Vallese, F. et al. (2022) Nature structural & molecular biology 29, 706-718. PMID: 35835865

9. Henderson, SW. et al. (2023) Biophysical reports 3, 100100. PMID: 36949749

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-AQP1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate

References

Datasheet

Anti-AQP1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-AQP1 Polyclonal Antibody (HB219014)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us