Anti-ARHGDIB Polyclonal Antibody (HW503014)

Name: Anti-ARHGDIB Polyclonal Antibody
Brand: abinScience
SKU: HW503014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW503014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human ARHGDIB (Asn66-Glu201).

Target

ARHGDIB, Rho-GDI beta, Rho GDP-dissociation inhibitor 2, RAP1GN1, Rho GDI 2, GDIA2, GDID4, Ly-GDI

Purification

Purified by antigen affinity column.

Accession

P52566

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Rho GDP-dissociation inhibitor 2 (ARHGDIB) is a ~22 kDa protein. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Regulates reorganization of the actin cytoskeleton mediated by Rho family members.

1. Adra, CN. et al. (1993) Genes, chromosomes & cancer 8, 253-61. PMID: 7512369

2. Scherle, P. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 7568-72. PMID: 8356058

3. Leffers, H. et al. (1993) Experimental cell research 209, 165-74. PMID: 8262133

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-ARHGDIB polyclonal antibody at 1µg/ml on various samples.
Lane 1: HL-60 cell lysate
Lane 2: Jurkat cell lysate
Lane 3: Raji cell lysate
Lane 4: THP-1 cell lysate
Lane 5: U937 cell lysate
Lane 6: Mouse spleen lysate
Lane 7: Mouse lung lysate
Lane 8: Rat spleen lysate