Anti-ASFV pM1249L Polyclonal Antibody (VK776014)

Name: Anti-ASFV pM1249L Polyclonal Antibody
Brand: abinScience
SKU: VK776014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

VK776014

Description

Anti-ASFV pM1249L Polyclonal Antibody (VK776014) is a rabbit polyclonal antibody detecting pM1249L in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

African swine fever virus (ASFV)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant ASFV pM1249L (Gln346-Pro452).

Target

Minor capsid protein M1249L, pM1249L, Ba71V-060, M1249L

Purification

Purified by antigen affinity column.

Accession

Q65152

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Minor capsid protein M1249L (pM1249L) is a ~144 kDa protein. Together with the penton and the other minor capsid proteins (p17, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid. In addition, blocks IFN-beta transactivation mediated by the cGAS-STING pathway and regulates the transcriptional activity of IFN-beta. Mechanistically, suppresses the phosphorylation of host key adapter protein TBK1 and degrades host IRF3 in the cytoplasm.

1. Wang, N. et al. (2019) Science (New York, N.Y.) 366, 640-644. PMID: 31624094

2. Cui, S. et al. (2022) Virus research 319, 198872. PMID: 35853521

Note

For research use only.

Images

References

Datasheet

Anti-ASFV pM1249L Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-ASFV pM1249L Polyclonal Antibody (VK776014)

Overview

Images

References

Datasheet

SDS

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