Anti-ATXN10 Polyclonal Antibody (HV718014)

Name: Anti-ATXN10 Polyclonal Antibody
Brand: abinScience
SKU: HV718014
Price: 96 USD
Availability: InStock

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Overview

Catalog No.

HV718014

Description

Anti-ATXN10 Polyclonal Antibody (HV718014) is a rabbit polyclonal antibody detecting ATXN10 in ELISA, IHC, WB. Suitable for Human, Bovine, Macaca fascicularis, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human ATXN10 (Leu116-Ala302).

Target

ATXN10, SCA10, Brain protein E46 homolog, Ataxin-10, Spinocerebellar ataxia type 10 protein

Purification

Purified by antigen affinity column.

Accession

Q9UBB4

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Ataxin-10 (ATXN10) is a ~53 kDa protein. May play a role in the regulation of cytokinesis. May play a role in signaling by stimulating protein glycosylation. Induces neuritogenesis by activating the Ras-MAP kinase pathway and is necessary for the survival of cerebellar neurons. Does not appear to play a major role in ciliogenesis.

1. Li, J. et al. (2011) Cell cycle (Georgetown, Tex.) 10, 2946-58. PMID: 21857149

2. Tian, J. et al. (2015) Scientific reports 5, 8360. PMID: 25666058

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-ATXN10 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: 293T cell lysate
Lane 3: HepG2 cell lysate
Lane 4: Jurkat cell lysate
Lane 5: SKOV3 cell lysate
Lane 6: HL-60 cell lysate

References

Datasheet

Anti-ATXN10 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-ATXN10 Polyclonal Antibody (HV718014)

Overview

Images

References

Datasheet

SDS

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