

| Catalog No. | HV085014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human BAIAP2 (Met1-Asn300). | ||||||||
| Target | BAI-associated protein 2, Insulin receptor substrate p53, IRS-58, BAI1-associated protein 2, IRSp53, Insulin receptor substrate p53/p58, Fas ligand-associated factor 3, BAIAP2, FLAF3, Insulin receptor substrate protein of 53 kDa, Brain-specific angiogenesis inhibitor 1-associated protein 2, Protein BAP2, IRSp53/58 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9UQB8 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | BAR/IMD domain-containing adapter protein 2 (IRSp53/BAIAP2) is a ~60 kDa protein. Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-BAIAP2 polyclonal antibody at 1ug/mL on recombinant BAIAP2 (Catalog No. HV085012).
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