

| Catalog No. | HV113014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-BCAS3 Polyclonal Antibody (HV113014) is a rabbit polyclonal antibody detecting BCAS3 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human BCAS3 (Met230-Gly546). | ||||||||
| Target | BCAS3, GAOB1, Breast carcinoma-amplified sequence 3 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9H6U6 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | BCAS3 microtubule associated cell migration factor is a ~101 kDa protein. Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation. Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. 1. Kojima, W. et al. (2021) Autophagy 17, 2011-2036. PMID: 33499712 | ||||||||
| Note | For research use only. |
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