Anti-BCCV Gn/Glycoprotein N Polyclonal Antibody (VK646024)

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Spec:

50ug
100ug

Number:

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK646024

Description

Anti-BCCV Gn/Glycoprotein N Polyclonal Antibody (VK646024) is a rabbit polyclonal antibody detecting Glycoprotein N in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Black Creek Canal orthohantavirus (BCCV) (Black Creek Canal virus)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant BCCV Gn/Glycoprotein N (Phe19-Val482).

Target

Envelopment polyprotein, Glycoprotein precursor, M polyprotein, Glycoprotein N, Gn, Glycoprotein G1, Glycoprotein C, Gc, Glycoprotein G2, GP

Purification

Purified by antigen affinity column.

Accession

P0DTJ0

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelopment polyprotein (Glycoprotein N/Gn) is a ~125 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. May dysregulate normal immune and endothelial cell responses through an ITAM motif.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-BCCV Gn/Glycoprotein N polyclonal antibody at 1ug/mL on recombinant BCCV Gn/Glycoprotein N (Catalog No. VK646022).

References

Datasheet