

| Catalog No. | HC468014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-BCL2L1 Polyclonal Antibody (HC468014) is a rabbit polyclonal antibody detecting BCL2L1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pig.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human BCL2L1 (Met1-Lys233). | ||||||||
| Target | BCL2L, Bcl-2-like protein 1, Apoptosis regulator Bcl-X, BCL2L1, Bcl2-L-1, BCLX | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q07817 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Bcl-2-like protein 1 (BCL2L1) is a ~26 kDa protein. Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. | ||||||||
| Note | For research use only. |
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