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Anti-BPV-1 VP3 Polyclonal Antibody (VK809014)

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Overview
Catalog No.VK809014
Description
Anti-BPV-1 VP3 Polyclonal Antibody (VK809014) is a rabbit polyclonal antibody detecting BPV-1 VP3. Suitable for Bovine parvovirus 1.
Species reactivityBovine parvovirus 1 (BPV-1)
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant BPV-1 VP3 (Gly178-Leu673).
Target EC:3.1.1.4, Minor capsid protein VP1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P07297
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Minor capsid protein VP1 (VP3) is a ~74 kDa protein. Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid. The capsid encapsulates the genomic ssDNA. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus.

Note For research use only
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Formula
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Anti-BPV-1 VP3 Polyclonal Antibody

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