

| Catalog No. | JN171014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Candida albicans HWP1 Polyclonal Antibody (JN171014) is a rabbit polyclonal antibody detecting HWP1. Suitable for Candida albicans.
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| Species reactivity | Candida albicans | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Candida albicans HWP1 (Thr305-Leu414). | ||||||||
| Target | Cell elongation protein 2, ECE2, HWP1, Hyphal wall protein 1 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P46593 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Hyphal wall protein 1 (HWP1) is a ~65 kDa protein. Major hyphal cell wall protein which plays a role of adhesin and is required for mating, normal hyphal development, cell-to-cell adhesive functions necessary for biofilm integrity, attachment to host, and virulence. Promotes interactions with host and bacterial molecules, thus leading to effective colonization within polymicrobial communities. Plays a crucial role in gastrointestinal colonization, in mucosal symptomatic and asymptomatic infections, in vaginitis, as well as in lethal oroesophageal candidiasis, caused by the combined action of fungal virulence factors and host inflammatory responses when protective immunity is absent. | ||||||||
| Note | For research use only |
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