Anti-CASP2 Polyclonal Antibody (HW804014)

Name: Anti-CASP2 Polyclonal Antibody
Brand: abinScience
SKU: HW804014
Price: 168 USD
Availability: InStock

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Overview
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SDS

Overview

Catalog No.

HW804014

Description

Anti-CASP2 Polyclonal Antibody (HW804014) is a rabbit polyclonal antibody detecting CASP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CASP2 (Gly334-Thr452).

Target

Protease ICH-1, ICH1, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD2, CASP-2, Caspase-2, CASP2, NEDD-2

Purification

Purified by antigen affinity column.

Accession

P42575

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Caspase-2 (CASP2) is a ~50 kDa protein. Is a regulator of the cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress.

1. Droin, N. et al. (2000) Cancer research 60, 7039-47. PMID: 11156409

2. Tinel, A. et al. (2004) Science (New York, N.Y.) 304, 843-6. PMID: 15073321

3. Wang, L. et al. (1994) Cell 78, 739-50. PMID: 8087842

Note

For research use only.

Images

References

Datasheet

Anti-CASP2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CASP2 Polyclonal Antibody (HW804014)

Overview

Images

References

Datasheet

SDS

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