Anti-CBY1 Polyclonal Antibody (HV591014)

Name: Anti-CBY1 Polyclonal Antibody
Brand: abinScience
SKU: HV591014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HV591014

Description

Anti-CBY1 Polyclonal Antibody (HV591014) is a rabbit polyclonal antibody detecting CBY1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CBY1 (Lys12-Glu115).

Target

ARPP-binding protein, PGEA1, CBY1, Protein chibby homolog 1, ARB1, CBY, PIGEA-14, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1, C22orf2, Cytosolic leucine-rich protein

Purification

Purified by antigen affinity column.

Accession

Q9Y3M2

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Protein chibby homolog 1 (CBY1) is a ~14 kDa protein. Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.

1. Takemaru, K. et al. (2003) Nature 422, 905-9. PMID: 12712206

2. Mofunanya, A. et al. (2009) BMC molecular biology 10, 41. PMID: 19435523

3. Hidaka, S. et al. (2004) The Journal of biological chemistry 279, 35009-16. PMID: 15194699

Note

For research use only.

Images

References

Datasheet

Anti-CBY1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CBY1 Polyclonal Antibody (HV591014)

Overview

Images

References

Datasheet

SDS

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