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Anti-CC2D1A Polyclonal Antibody (HV164014)

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Overview
Catalog No.HV164014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human CC2D1A (Pro675-Ser944).
Target AKI1, Five prime repressor element under dual repression-binding protein 1, Akt kinase-interacting protein 1, Freud-1, Coiled-coil and C2 domain-containing protein 1A, FRE under dual repression-binding protein 1, Putative NF-kappa-B-activating protein 023N, CC2D1A
Purification Purified by antigen affinity column.
Accession Q6P1N0
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Coiled-coil and C2 domain-containing protein 1A (CC2D1A) is a ~104 kDa protein. Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses.

Note For research use only.
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Formula
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Anti-CC2D1A Polyclonal Antibody

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