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Anti-CCN4 Polyclonal Antibody (HF984014)

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Overview
Catalog No.HF984014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human CCN4 (Cys216-Arg347).
Target WNT1-inducible-signaling pathway protein 1, WISP-1, Wnt-1-induced secreted protein, CCN4, WISP1, CCN family member 4
Purification Purified by antigen affinity column.
Accession O95388
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

CCN family member 4 (CCN4/WISP-1) is a ~40 kDa protein. Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts.

Note For research use only.
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