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Anti-CD181/CD128/CXCR1 Polyclonal Antibody (HB839014)

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Overview
Catalog No.HB839014
Description
Anti-CD181/CD128/CXCR1 Polyclonal Antibody (HB839014) is a rabbit polyclonal antibody detecting CD181 in ELISA, IHC, WB. Suitable for Human, Hoolock hoolock, Macaca mulatta, Pan troglodytes, and Pongo pygmaeus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human CD181/CD128/CXCR1 (Asp265-Leu350).
Target IL-8 receptor type 1, CDw128a, CD181, IL8RA, IL-8R A, High affinity interleukin-8 receptor A, CXCR-1, CXCR1, C-X-C chemokine receptor type 1, CXC-R1, CMKAR1
Purification Purified by antigen affinity column.
Accession P25024
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

C-X-C chemokine receptor type 1 (CD181/CD128) is a ~39 kDa protein. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.

1. Holmes, WE. et al. (1991) Science (New York, N.Y.) 253, 1278-80. PMID: 1840701
2. Damaj, BB. et al. (1996) The Journal of biological chemistry 271, 12783-9. PMID: 8662698
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-CD181/CD128/CXCR1 Polyclonal Antibody

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