Anti-CD20/MS4A1 Polyclonal Antibody (HY257014)

Name: Anti-CD20/MS4A1 Polyclonal Antibody
Brand: abinScience
SKU: HY257014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HY257014

Description

Anti-CD20/MS4A1 Polyclonal Antibody (HY257014) is a rabbit polyclonal antibody detecting MS4A1 in ELISA, IHC, WB, IF. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB, IF

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD20/MS4A1 (Ile143-Ser188).

Target

B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P11836

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

B-lymphocyte antigen CD20 (MS4A1) is a ~33 kDa protein. B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. CD20 is the therapeutic target of rituximab (MabThera) and obinutuzumab (Gazyva).

1. Li, H. et al. (2003) The Journal of biological chemistry 278, 42427-34. PMID: 12920111

2. Tedder, TF. et al. (1985) Journal of immunology (Baltimore, Md. : 1950) 135, 973-9. PMID: 3925015

3. Bubien, JK. et al. (1993) The Journal of cell biology 121, 1121-32. PMID: 7684739

4. Polyak, MJ. et al. (2008) The Journal of biological chemistry 283, 18545-52. PMID: 18474602

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CD20/MS4A1 polyclonal antibody at 1ug/mL on recombinant CD20/MS4A1 (Catalog No. HY257022).

References

Datasheet