Anti-CD244 Polyclonal Antibody (HV513014)

Name: Anti-CD244 Polyclonal Antibody
Brand: abinScience
SKU: HV513014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV513014

Description

Anti-CD244 Polyclonal Antibody (HV513014) is a rabbit polyclonal antibody detecting CD244 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD244 (Cys22-Pro229).

Target

SLAM family member 4, SLAMF4, h2B4, Signaling lymphocytic activation molecule 4, Natural killer cell receptor 2B4, NKR2B4, NAIL, NK cell type I receptor protein 2B4, CD244, NK cell activation-inducing ligand, 2B4

Purification

Purified by antigen affinity column.

Accession

Q9BZW8

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Natural killer cell receptor 2B4 (CD244) is a ~41 kDa protein. Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor. Activating function implicates association with SH2D1A and FYN.

1. Nakajima, H. et al. (1999) European journal of immunology 29, 1676-83. PMID: 10359122

2. Speiser, DE. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 6165-70. PMID: 11714776

3. Valiante, NM. et al. (1993) The Journal of experimental medicine 178, 1397-406. PMID: 8376943

4. Eissmann, P. et al. (2005) Blood 105, 4722-9. PMID: 15713798

5. Parolini, S. et al. (2000) The Journal of experimental medicine 192, 337-46. PMID: 10934222

6. Sivori, S. et al. (2000) European journal of immunology 30, 787-93. PMID: 10741393

7. Sivori, S. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 4526-31. PMID: 11917118

Note

For research use only.

Images

References

Datasheet

Anti-CD244 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CD244 Polyclonal Antibody (HV513014)

Overview

Images

References

Datasheet

SDS

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