Anti-CD273/PD-L2/PDCD1LG2 Polyclonal Antibody (HV809014)

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50ug
100ug

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV809014

Description

Anti-CD273/PD-L2/PDCD1LG2 Polyclonal Antibody (HV809014) is a rabbit polyclonal antibody detecting PD-L2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD273/PD-L2/PDCD1LG2 (Leu20-Thr220).

Target

PDCD1 ligand 2, B7-DC, PD-L2, PDCD1LG2, PDCD1L2, PDL2, Butyrophilin B7-DC, Programmed death ligand 2, Programmed cell death 1 ligand 2, CD273, B7DC, PD-1 ligand 2

Purification

Purified by antigen affinity column.

Accession

Q9BQ51

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Programmed cell death 1 ligand 2 (CD273/PD-L2) is a ~30 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production.

1. Latchman, Y. et al. (2001) Nature immunology 2, 261-8. PMID: 11224527

2. Brown, JA. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 1257-66. PMID: 12538684

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CD273/PD-L2/PDCD1LG2 polyclonal antibody at 1ug/mL on recombinant CD273/PD-L2/PDCD1LG2 (Catalog No. HV809012).

References

Datasheet