

| Catalog No. | HY286073 | ||||
|---|---|---|---|---|---|
| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Human | ||||
| Isotype | scFv-His | ||||
| Clone ID | SAA2245 | ||||
| Expression system | Mammalian cells | ||||
| Clonality | Monoclonal | ||||
| Target | CD340/ERBB2/HER2 | ||||
| Specificity | Human | ||||
| Purity | >95% purity as determined by SDS-PAGE. | ||||
| Accession | P04626 | ||||
| RRID | Anti-CD340/ERBB2/HER2 scFV Antibody (SAA2245) (abinScience Cat# HY286073, RRID:AB_3730101) |
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| Form | Liquid | ||||
| Product Usage Information |
| ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. | ||||
| Alternate Names | Epidermal growth factor receptor, EC:2.7.10.1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR | ||||
| Background | Receptor tyrosine-protein kinase erbB-2 (CD340/ERBB2) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-CD340/ERBB2/HER2 scFV Antibody (SAA2245).
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