Anti-CDC42 Polyclonal Antibody (HX069014)

Name: Anti-CDC42 Polyclonal Antibody
Brand: abinScience
SKU: HX069014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

HX069014

Description

Anti-CDC42 Polyclonal Antibody (HX069014) is a rabbit polyclonal antibody detecting CDC42 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Aedes aegypti.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CDC42 (Met1-Cys188).

Target

CDC42, G25K GTP-binding protein, Cell division control protein 42 homolog

Purification

Purified by antigen affinity column.

Accession

P60953

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Cell division control protein 42 homolog (CDC42) is a ~21 kDa protein. Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration.

1. Oceguera-Yanez, F. et al. (2005) The Journal of cell biology 168, 221-32. PMID: 15642749

2. Modzelewska, K. et al. (2006) The Journal of biological chemistry 281, 37527-35. PMID: 17038317

3. Hong, IK. et al. (2012) The Journal of biological chemistry 287, 32027-39. PMID: 22843693

4. Gauthier-Campbell, C. et al. (2004) Molecular biology of the cell 15, 2205-17. PMID: 14978216

5. Majmundar, AJ. et al. (2021) Science advances 7. PMID: 33523862

6. Schlam, D. et al. (2015) Nature communications 6, 8623. PMID: 26465210

7. Ninomiya, K. et al. (2021) Journal of cell science 134. PMID: 33310911

Note

For research use only.

Images

References

Datasheet

Anti-CDC42 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CDC42 Polyclonal Antibody (HX069014)

Overview

Images

References

Datasheet

SDS

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