

| Catalog No. | HA548014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Cerebellin-2/CBLN2 Polyclonal Antibody (HA548014) is a rabbit polyclonal antibody detecting Cerebellin-2/CBLN2 in WB, IHC, ELISA. Suitable for Human, Mus musculus, Rattus norvegicus, Bovine, and Sus scrofa.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | WB, IHC, ELISA | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Cerebellin-2/CBLN2 (Gly89-Leu224). | ||||||||
| Target | Cerebellin-2/CBLN2 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purity | >90% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q8IUK8 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Alternate Names | Cerebellin-2, CBLN2 | ||||||||
| Background | Cerebellin-2 (CBLN2) is a ~24 kDa protein. Acts as a synaptic organizer in specific subsets of neurons in the brain. Essential for long-term maintenance but not establishment of excitatory synapses. Functions as part of a trans-synaptic complex by binding to postsynaptic GRID1 and presynaptic neurexins. This interaction helps regulate the activity of NMDA and AMPA receptors at hippocampal synapses without affecting synapse formation. NRXN1B-CBLN2-GRID1 complex transduce presynaptic signals into postsynaptic NMDAR response. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-CBLN2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat brain lysate



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