

| Catalog No. | HY356014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-CETP Polyclonal Antibody (HY356014) is a rabbit polyclonal antibody detecting CETP in ELISA, IHC, WB. Suitable for Human and Macaca fascicularis.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human CETP (Ile81-Ala311). | ||||||||
| Target | CETP, Lipid transfer protein I, Cholesteryl ester transfer protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P11597 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Cholesteryl ester transfer protein (CETP) is a ~54 kDa protein. Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination. 1. Morton, RE. et al. (2014) Journal of lipid research 55, 258-65. PMID: 24293641 2. Hesler, CB. et al. (1988) The Journal of biological chemistry 263, 5020-3. PMID: 3281933 3. Drayna, D. et al. (1987) Nature 327, 632-4. PMID: 3600759 4. Qiu, X. et al. (2007) Nature structural & molecular biology 14, 106-13. PMID: 17237796 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-CETP polyclonal antibody at 1ug/mL on various samples.
Lane 1: HT-29 cell lysate
Lane 2: MCF-7 cell lysate
Lane 3: A375 cell lysate
Lane 4: Hela cell lysate
Lane 5: Mouse liver lysate
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