Anti-CFL2 Polyclonal Antibody (HV067014)

Name: Anti-CFL2 Polyclonal Antibody
Brand: abinScience
SKU: HV067014
Price: 96 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV067014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CFL2 (Ala2-Leu166).

Target

CFL2, Cofilin-2, Cofilin, muscle isoform

Purification

Purified by antigen affinity column.

Accession

Q9Y281

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Cofilin-2 (CFL2) is a ~18 kDa protein. Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance.

1. Papalouka, V. et al. (2009) Molecular and cellular biology 29, 6046-58. PMID: 19752190

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CFL2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Raji cell lysate
Lane 2: Mouse brain lysate
Lane 3: Mouse lung lysate
Lane 4: Rat brain lysate
Lane 5: Rat lung lysate
Lane 6: Rat skeletal muscle lysate