Anti-CFP Polyclonal Antibody (HB792014)

Name: Anti-CFP Polyclonal Antibody
Brand: abinScience
SKU: HB792014
Price: 96 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB792014

Description

Anti-CFP Polyclonal Antibody (HB792014) is a rabbit polyclonal antibody detecting CFP in ELISA, IHC, WB. Suitable for Human and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CFP (Gln65-Cys190).

Target

PFC, CFP, Properdin, Complement factor P

Purification

Purified by antigen affinity column.

Accession

P27918

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Properdin (CFP) is a ~51 kDa protein. A positive regulator of the alternate pathway (AP) of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b).

1. Hourcade, DE. (2006) The Journal of biological chemistry 281, 2128-32. PMID: 16301317

2. Ferreira, VP. et al. (2010) Immunobiology 215, 932-40. PMID: 20382442

3. Pedersen, DV. et al. (2017) The EMBO journal 36, 1084-1099. PMID: 28264884

4. Hourcade, DE. et al. (1998) The Journal of biological chemistry 273, 25996-6000. PMID: 9748277

5. Pedersen, DV. et al. (2019) Frontiers in immunology 10, 2007. PMID: 31507604

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CFP polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate