

| Catalog No. | GY328014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Chicken IL6 Polyclonal Antibody (GY328014) is a rabbit polyclonal antibody detecting IL6 in WB, IHC, ELISA. Suitable for Chicken.
Highlights
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| Species reactivity | Chicken | ||||||||
| Applications | WB, IHC, ELISA | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Chicken IL6 (Val47-Ala241). | ||||||||
| Target | IL6 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purity | >90% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q90YI0 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Alternate Names | Interleukin-6, ChIL-6, IL-6, IL6 | ||||||||
| Background | Interleukin-6 (IL6) is a ~26 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells. IL6 is the therapeutic target of tocilizumab (Actemra). | ||||||||
| Note | For research use only. |
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