Anti-CLIC3 Polyclonal Antibody (HB593014)

Name: Anti-CLIC3 Polyclonal Antibody
Brand: abinScience
SKU: HB593014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HB593014

Description

Anti-CLIC3 Polyclonal Antibody (HB593014) is a rabbit polyclonal antibody detecting Chloride intracellular channel protein 3; CLIC3 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant human CLIC3 (Asp45-Arg236).

Target

Chloride intracellular channel protein 3; CLIC3

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

O95833, Q9D7P7

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Chloride intracellular channel protein 3 (CLIC3) is a ~26 kDa protein. In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Reduced in a glutathione-dependent way and secreted into the extracellular matrix where it activates TGM2 and promotes blood vessel growth during tissue remodeling as occurs in tumorigenesis. Can reduce specific cysteines in TGM2 and regulate cofactor binding. Can insert into membranes and form outwardly rectifying chloride ion channels. May participate in cellular growth control.

1. Hernandez-Fernaud, JR. et al. (2017) Nature communications 8, 14206. PMID: 28198360

2. Alghalayini, A. et al. (2023) Biomolecules 13. PMID: 37759794

Note

For research use only

Images

References

Datasheet

Anti-CLIC3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CLIC3 Polyclonal Antibody (HB593014)

Overview

Images

References

Datasheet

SDS