

| Catalog No. | HB672014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human COL8A1 (Pro575-Pro743). | ||||||||
| Target | COL8A1, Endothelial collagen, C3orf7, Collagen alpha-1(VIII) chain | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P27658 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Collagen alpha-1(VIII) chain (COL8A1) is a ~73 kDa protein. Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also a component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-COL8A1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: HepG2 cell lysate
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