Anti-CPSF1 Polyclonal Antibody (HB486014)

Name: Anti-CPSF1 Polyclonal Antibody
Brand: abinScience
SKU: HB486014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

HB486014

Description

Anti-CPSF1 Polyclonal Antibody (HB486014) is a rabbit polyclonal antibody detecting Cleavage and polyadenylation specificity factor subunit 1; Cleavage and polyadenylation specificity factor 160 kDa subunit; CPSF 160 kDa subunit; CPSF1; CPSF160 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Zebrafish.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Bovine, Zebrafish

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant human CPSF1 (Thr1021-Phe1443).

Target

Cleavage and polyadenylation specificity factor subunit 1; Cleavage and polyadenylation specificity factor 160 kDa subunit; CPSF 160 kDa subunit; CPSF1; CPSF160

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q10570, Q9EPU4, Q10569, A0A0R4IC37

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Cleavage and polyadenylation specificity factor subunit 1 (CPSF1) is a ~160 kDa protein. Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction. May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain.

1. Kaufmann, I. et al. (2004) The EMBO journal 23, 616-26. PMID: 14749727

Note

For research use only

Images

References

Datasheet

Anti-CPSF1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CPSF1 Polyclonal Antibody (HB486014)

Overview

Images

References

Datasheet

SDS

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