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Anti-CPV2/FPV Capsid protein VP1 Recombinant Antibody (SAA2338) (VK761043)

Anti-CPV2/FPV Capsid protein VP1 Recombinant Antibody (SAA2338)
Anti-CPV2/FPV Capsid protein VP1 Recombinant Antibody (SAA2338)
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Overview
Catalog No.VK761043
Species reactivityCanine parvovirus type 2 (CPV2), Feline panleukopenia virus (FPV)
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA2338
Clonality Monoclonal
Target Capsid protein VP1, Coat protein VP1,
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P17455, P04864
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Capsid protein VP1 is a ~80 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptor TFRC. This attachment induces virion internalization predominantly through clathrin-endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and nuclear localization signal(s).

Note For research use only
Images
  • Anti-CPV2/FPV Capsid protein VP1 Recombinant Antibody (SAA2338)

    SDS-PAGE

    SDS-PAGE for Anti-CPV2/FPV Capsid protein VP1 Antibody (SAA2338)

References
Formula
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