Anti-CRMP1 Polyclonal Antibody (HC596014)

Name: Anti-CRMP1 Polyclonal Antibody
Brand: abinScience
SKU: HC596014
Price: 96 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC596014

Description

Anti-CRMP1 Polyclonal Antibody (HC596014) is a rabbit polyclonal antibody detecting CRMP1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CRMP1 (Met1-Val250).

Target

ULIP-3, Inactive dihydropyrimidinase, CRMP1, DPYSL1, DRP-1, Dihydropyrimidinase-related protein 1, ULIP3, Collapsin response mediator protein 1, Unc-33-like phosphoprotein 3, CRMP-1

Purification

Purified by antigen affinity column.

Accession

Q14194

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Dihydropyrimidinase-related protein 1 (CRMP1) is a ~62 kDa protein. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis.

1. Nakamura, F. et al. (2014) Nature communications 5, 5325. PMID: 25358863

2. Shih, JY. et al. (2001) Journal of the National Cancer Institute 93, 1392-400. PMID: 11562390

3. Chen, TC. et al. (2009) Journal of proteome research 8, 4943-53. PMID: 19799413

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CEMP1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse Cerebellum lysate
Lane 3: Rat brain lysate
Lane 4: Rat Cerebellum lysate