Anti-CSNK1A1 Polyclonal Antibody (HW510014)

Name: Anti-CSNK1A1 Polyclonal Antibody
Brand: abinScience
SKU: HW510014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HW510014

Description

Anti-CSNK1A1 Polyclonal Antibody (HW510014) is a rabbit polyclonal antibody detecting CSNK1A1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CSNK1A1 (Lys130-Phe337).

Target

CK1, Casein kinase I isoform alpha, CSNK1A1, CKI-alpha

Purification

Purified by antigen affinity column.

Accession

P48729

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Casein kinase I isoform alpha (CSNK1A1) is a ~38 kDa protein. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2.

1. Liu, C. et al. (2002) Cell 108, 837-47. PMID: 11955436

2. Brockman, JL. et al. (1992) Proceedings of the National Academy of Sciences of the United States of America 89, 9454-8. PMID: 1409656

3. Gonzales, ML. et al. (2008) The Journal of biological chemistry 283, 12665-73. PMID: 18305108

4. Kuga, T. et al. (2013) Journal of cell science 126, 4721-31. PMID: 23902688

5. Gao, D. et al. (2011) Molecular cell 44, 290-303. PMID: 22017875

6. Duan, S. et al. (2011) Molecular cell 44, 317-24. PMID: 22017877

Note

For research use only.

Images

References

Datasheet

Anti-CSNK1A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CSNK1A1 Polyclonal Antibody (HW510014)

Overview

Images

References

Datasheet

SDS

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