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Anti-CTDSPL Polyclonal Antibody (HT431014)

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Overview
Catalog No.HT431014
Description
Anti-CTDSPL Polyclonal Antibody (HT431014) is a rabbit polyclonal antibody detecting CTDSPL in ELISA, IHC, WB. Suitable for Chicken, Human, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human CTDSPL (Pro13-Val236).
Target hYA22, CTD small phosphatase-like protein, YA22, NIFL, NLI-interacting factor 1, RBSP3, SCP3, Small CTD phosphatase 3, CTDSP-like, Nuclear LIM interactor-interacting factor 1, Protein YA22, NIF-like protein, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, C3orf8, NIF1, CTDSPL, Small C-terminal domain phosphatase 3
Purification Purified by antigen affinity column.
Accession O15194
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

CTD small phosphatase-like protein (CTDSPL) is a ~31 kDa protein. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.

Note For research use only.
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Formula
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Anti-CTDSPL Polyclonal Antibody

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