Anti-CTSD Polyclonal Antibody (HY168014)

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Overview

Catalog No.

HY168014

Description

Anti-CTSD Polyclonal Antibody (HY168014) is a rabbit polyclonal antibody detecting CTSD in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Dog, Rat, Bos taurus, Ovis aries

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CTSD (Arg23-Gln161).

Target

CPSD, CTSD, Cathepsin D

Purification

Purified by antigen affinity column.

Accession

P07339

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Cathepsin D (CTSD) is a ~44 kDa protein. Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

1. Letronne, F. et al. (2016) EBioMedicine 9, 278-292. PMID: 27333034

Note

For research use only.

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