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Anti-D. melanogaster SLC6A3/DAT Recombinant Antibody (9D5) (ZX986013)

Anti-D. melanogaster SLC6A3/DAT Recombinant Antibody (9D5)
Anti-D. melanogaster SLC6A3/DAT Recombinant Antibody (9D5)
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Overview
Catalog No.ZX986013
Species reactivityDrosophila melanogaster (Fruit fly)
ApplicationsIF
Host speciesMouse
IsotypeIgG
Clone ID9D5
Clonality Monoclonal
Target Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3, SLC6A3, DAT1
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q7K4Y6
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Sodium-dependent dopamine transporter (DAT) is a ~70 kDa protein. Sodium-dependent dopamine transporter which terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. Also transports tyramine and norepinephrine, shows less efficient transport of octopamine and does not transport serotonin. Plays a role in the regulation of the rest/activity cycle.

1. Pörzgen, P. et al. (2001) Molecular pharmacology 59, 83-95. PMID: 11125028
2. Wu, X. et al. (2003) Molecular pharmacology 63, 653-8. PMID: 12606774
3. Penmatsa, A. et al. (2013) Nature 503, 85-90. PMID: 24037379
4. Wang, KH. et al. (2015) Nature 521, 322-7. PMID: 25970245
5. Kume, K. et al. (2005) The Journal of neuroscience : the official journal of the Society for Neuroscience 25, 7377-84. PMID: 16093388
6. Ueno, T. et al. (2014) Frontiers in behavioral neuroscience 8, 303. PMID: 25232310
Note For research use only
Images
  • Anti-D. melanogaster SLC6A3/DAT Recombinant Antibody (9D5)

    SDS-PAGE

    SDS-PAGE for Anti-D. melanogaster SLC6A3/DAT Antibody (9D5)

References
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