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Anti-DPYD Polyclonal Antibody (HC616014)

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Overview
Catalog No.HC616014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human DPYD (Ile781-Cys1025).
Target Dihydropyrimidine dehydrogenase [NADP(+)], DPYD, DPD, Dihydrouracil dehydrogenase, Dihydrothymine dehydrogenase, DHPDHase
Purification Purified by antigen affinity column.
Accession Q12882
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Dihydropyrimidine dehydrogenase [NADP(+)] (DPYD) is a ~111 kDa protein. Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.

1. Lu, ZH. et al. (1992) The Journal of biological chemistry 267, 17102-9. PMID: 1512248
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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C₂ (Working Conc.)
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Anti-DPYD Polyclonal Antibody

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